They dont frustratingly get away sometimes like in real life.








Equities research analysts at FBN Securities upgraded shares of Research In Motion (NASDAQ: RIMM) from a “sell” rating to an “outperform” rating in a research note to clients and investors on Tuesday.


Separately, analysts at BNP Paribas (EPA: BNP) downgraded shares of Research In Motion from an “outperform” rating to a “neutral” rating in a research note to investors on Monday.


Research In Motion Limited (RIM) is a designer, manufacturer and marketer of wireless solutions for the worldwide mobile communications market. Through the development of integrated hardware, software and services that support multiple wireless network standards, RIM provides platforms and solutions for seamless access to time-sensitive information, including e-mail, phone, short message service (SMS), Internet and intranet-based applications. RIM’s portfolio of products, services and embedded technologies are used by organizations worldwide and include the BlackBerry wireless solution, the RIM Wireless Handheld product line, software development tools and other software and hardware. Its subsidiaries include Research In Motion Corporation, Research In Motion UK Limited and RIM Finance, LLC. On June 2, 2010, Harman International sold its software operating systems unit, QNX Software Systems, to the Company.


Shares of Research In Motion (NASDAQ: RIMM) traded down 2.38% during mid-day trading on Wednesday, hitting $59.01. Research In Motion has a 52 week low of $42.53 and a 52 week high of $76.95. The stock’s 50-day moving average is $58.48 and its 200-day moving average is $53.50. On average, analysts predict that Research In Motion will post $1.61 EPS next quarter. The company has a market cap of $30.846 billion and a price-to-earnings ratio of 11.64.











IP/10/252

Brussels, 9 th March 2010

European Commission unveils new research projects to fight influenza

Today, the European Commission has announced the results of its €18 million call for proposals for new research projects on influenza. Four collaborative research projects have been shortlisted for funding. They involve 52 research institutes and SMEs from 18 European countries and 3 international partners (Israel, China, the United States). Influenza virus genes migrate across continents and between species and seriously threaten both human and animal health. Two consortia will focus their research on influenza in pigs while the two others will develop innovative drugs against influenza in humans. Their selection is part of the EU's longstanding support for research on influenza and brings the total Commission funding in this field to over €100 million since 2001.

EU Commissioner for Research, Innovation and Science Máire Geoghegan-Quinn said: "Seasonal flu alone can kill 250,000 – 500,000 people worldwide every year and EU-funded research projects like these can help save lives. What is more, successful EU research in preventing and treating flu and other diseases has enormous social and economic value and can contribute significantly to our Europe 2020 goals".

Next steps

Final EU contribution per project and project details will be subject to the signature of contracts which should take place in 2010.

Background

The €18 million call for proposals for new research projects on influenza was launched in July 2009. 17 proposals were submitted.

Details of new influenza research projects announced today – more information and scientific background on the projects below at:

http://ec.europa.eu/research/index.cfm?pg=newsalert&lg=en&year=2010&na=na-090310-annexes

ESNIP 3 - European surveillance network for influenza in pigs 3

This ESNIP 3 project will maintain and expand the surveillance network for influenza in pigs established during the previous EU funded projects ESNIP 1 and ESNIP 2 which represented the only organised surveillance network of this kind. The project is expected to contribute to improved pandemic preparedness and planning for human influenza and provide an evidence base for decisions in relation to veterinary health.

Duration: 36 months

Expected EU contribution: €1 million

Coordinator: Ian Brown, The Veterinarian Laboratories Agency (United Kingdom), i.h.brown@vla.defra.gsi.gov.uk .

Contact for the press: Jane Goodger, j.goodger@vla.defra.gsi.gov.uk

25 Partners from 15 countries: United Kingdom, Belgium, France, Italy, Denmark, Poland, Spain, Germany, Finland, Hungary, The Netherlands, Greece, Israel, China and the United States.

FLUPIG - Pathogenesis and transmission of influenza virus in pigs

This project aims at a better understanding of the role of pigs in influenza pandemics. The exact role of pigs is unclear, as is the nature of the genetic changes that are required for (a) efficient replication of an avian virus in pigs, (b) efficient transmission of avian viruses between pigs and (c) virus transmission from pigs to humans and between humans. More knowledge of this will be critical to the control of future influenza pandemics

Duration: 48 months

Expected EU contribution: €5 million

Coordinator: Kristien van Reeth, Faculty of Veterinary Medicine, Ghent University, (Belgium), kristien.vanreeth@ugent.be

10 Partners from 8 countries: Belgium, Italy, United Kingdom, Germany, The Netherlands, Poland, China (Hong-Kong) and the United States.

FLU-PHARM - New drugs targeting influenza virus

The project FLU-PHARM will develop new drug candidates that inhibit viral replication in infected cells (by targeting the PB2 and PA protein domains). Such drugs are expected to have a reduced risk of patients developing resistance to them and less undesirable side-effects. If successful, FLU-PHARM will provide new opportunities for treating both seasonal and pandemic flu.

Duration: 42 months

Expected EU contribution: €6 million

Coordinator: Stephen Cusack, European Molecular Biology Laboratory (France) cusack@embl.fr

14 Partners from 7 countries: Germany, Austria, France, Spain, Slovakia, Belgium, Sweden

FLUCURE - Development of novel antiviral drugs against Influenza

The FLUCURE project will also targets the viral replication machinery (with a different approach as it will target the PB1/PA proteins and NP proteins) and aims to develop new drug candidates with reduced risk of resistance. The objective is to deliver one or more drug candidates suitable for entering clinical development within four years.

Duration: 48 months

Expected EU contribution: €6 million

Coordinator: Heather Marshall-Heyman, VIRONOVA AB (Sweden), heather.marshall-heyman@vironova.com

9 Partners from 7 European countries: Sweden, Switzerland, Bulgaria, The Netherlands, Lithuania, Germany, Italy





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IP/10/252

Brussels, 9 th March 2010

European Commission unveils new research projects to fight influenza

Today, the European Commission has announced the results of its €18 million call for proposals for new research projects on influenza. Four collaborative research projects have been shortlisted for funding. They involve 52 research institutes and SMEs from 18 European countries and 3 international partners (Israel, China, the United States). Influenza virus genes migrate across continents and between species and seriously threaten both human and animal health. Two consortia will focus their research on influenza in pigs while the two others will develop innovative drugs against influenza in humans. Their selection is part of the EU's longstanding support for research on influenza and brings the total Commission funding in this field to over €100 million since 2001.

EU Commissioner for Research, Innovation and Science Máire Geoghegan-Quinn said: "Seasonal flu alone can kill 250,000 – 500,000 people worldwide every year and EU-funded research projects like these can help save lives. What is more, successful EU research in preventing and treating flu and other diseases has enormous social and economic value and can contribute significantly to our Europe 2020 goals".

Next steps

Final EU contribution per project and project details will be subject to the signature of contracts which should take place in 2010.

Background

The €18 million call for proposals for new research projects on influenza was launched in July 2009. 17 proposals were submitted.

Details of new influenza research projects announced today – more information and scientific background on the projects below at:

http://ec.europa.eu/research/index.cfm?pg=newsalert&lg=en&year=2010&na=na-090310-annexes

ESNIP 3 - European surveillance network for influenza in pigs 3

This ESNIP 3 project will maintain and expand the surveillance network for influenza in pigs established during the previous EU funded projects ESNIP 1 and ESNIP 2 which represented the only organised surveillance network of this kind. The project is expected to contribute to improved pandemic preparedness and planning for human influenza and provide an evidence base for decisions in relation to veterinary health.

Duration: 36 months

Expected EU contribution: €1 million

Coordinator: Ian Brown, The Veterinarian Laboratories Agency (United Kingdom), i.h.brown@vla.defra.gsi.gov.uk .

Contact for the press: Jane Goodger, j.goodger@vla.defra.gsi.gov.uk

25 Partners from 15 countries: United Kingdom, Belgium, France, Italy, Denmark, Poland, Spain, Germany, Finland, Hungary, The Netherlands, Greece, Israel, China and the United States.

FLUPIG - Pathogenesis and transmission of influenza virus in pigs

This project aims at a better understanding of the role of pigs in influenza pandemics. The exact role of pigs is unclear, as is the nature of the genetic changes that are required for (a) efficient replication of an avian virus in pigs, (b) efficient transmission of avian viruses between pigs and (c) virus transmission from pigs to humans and between humans. More knowledge of this will be critical to the control of future influenza pandemics

Duration: 48 months

Expected EU contribution: €5 million

Coordinator: Kristien van Reeth, Faculty of Veterinary Medicine, Ghent University, (Belgium), kristien.vanreeth@ugent.be

10 Partners from 8 countries: Belgium, Italy, United Kingdom, Germany, The Netherlands, Poland, China (Hong-Kong) and the United States.

FLU-PHARM - New drugs targeting influenza virus

The project FLU-PHARM will develop new drug candidates that inhibit viral replication in infected cells (by targeting the PB2 and PA protein domains). Such drugs are expected to have a reduced risk of patients developing resistance to them and less undesirable side-effects. If successful, FLU-PHARM will provide new opportunities for treating both seasonal and pandemic flu.

Duration: 42 months

Expected EU contribution: €6 million

Coordinator: Stephen Cusack, European Molecular Biology Laboratory (France) cusack@embl.fr

14 Partners from 7 countries: Germany, Austria, France, Spain, Slovakia, Belgium, Sweden

FLUCURE - Development of novel antiviral drugs against Influenza

The FLUCURE project will also targets the viral replication machinery (with a different approach as it will target the PB1/PA proteins and NP proteins) and aims to develop new drug candidates with reduced risk of resistance. The objective is to deliver one or more drug candidates suitable for entering clinical development within four years.

Duration: 48 months

Expected EU contribution: €6 million

Coordinator: Heather Marshall-Heyman, VIRONOVA AB (Sweden), heather.marshall-heyman@vironova.com

9 Partners from 7 European countries: Sweden, Switzerland, Bulgaria, The Netherlands, Lithuania, Germany, Italy





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And how do you make that traffic a highly targeted traffic?


The Seattle Biomedical Research Institute is doing research on malaria vaccines. They are wanting to find out if the vaccines work. Since they do not know if the vaccines work, they are looking for volunteers who will try the vaccines and then hold a cup of mosquitoes that are infected with the most deadly form of malaria to their arm so they are bitten. This study is a continuation of a study that start at Walter Reed Army Institute of Maryland is is funded by the Bill and Melinda Gates Foundation.

Since people are being asked to be infected with malaria, this brings up all kinds of ethical questions. First of all, would these people get seriously ill and even die? According to the researchers this would not happen and people would only have flu like symptoms for about a single day.

However, while the researchers may be able to try to control the mosquitoes to the best of their abilities, it is uncertain that these people may not have some type of allergic reaction or end up getting some type of disease or other infection from the mosquitoes.

Also, would malaria spread if these people are out in the community? Researchers say that the malaria will not get to a point where it is infectious from person to person. Most likely this is true since they know the research that has already been happening.

Of course, the volunteers are given $2,000 for participating. The researchers have said that this is mainly compensation for missing work or replacing funds used to get to the site and any other costs volunteers may incur.

While this sounds a little bit on the dangerous sides, there are benefits as a whole. People really do care about others in third world country who are often infected with malaria and do not survive because vaccines do not exist and they cannot afford the medication. Thus, people who want to make sure that vaccines will be available to these people may have an urge to volunteer for this program.

While I like the idea of getting vaccines to people in third world countries, no amount of money would make me go get a vaccine that may or may not work and be infected with a possibly deadly disease. While I know that only flu like symptoms should occur, I would be scared that something would go wrong.

I want to live my life and not be willingly infected with a disease. I would be scared that I'd have something in my body or have some type of reaction either to the vaccine or to the disease that would end my life suddenly.

While I know that I can't control the length of my own life, I can try to take care of myself so I have a good life. I want to be able to spend time with my friends, my family, and my dog. If anything were to happen because of this, the money, no matter how much of an amount, would not do me any good. While it could help my family, it would not ease the pain of the loss.

I'd rather earn my money honestly than making myself into a medical guinea pig.





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research paper outline


Patricia L. Sullivan, an assistant professor at the University of Georgia's School of Public and International Affairs recently completed a study advancing a new model which predicts a nation's probability of accomplishing military objectives. Sullivan's research, reported in the June issue of the Journal of Conflict Resolution and by the UGA Office of Public Affairs News Service, found that since WWII major countries, including the United States, the Soviet Union, Russia, China, Britain or France, have failed in 39% of 122 military objectives against smaller, weaker nations.

Under a grant funded by the National Science Foundation and institute on Global Conflict and Cooperation Sullivan conducted research to explain the "circumstances under which more powerful nations are likely to fail and creates a model that allows policymakers to calculate the probability of success in current and future conflicts, "according to the UGA News Service.

Factors which Sullivan found important are the objective, the nature of the target, whether or not the target cooperates with the objective, whether the target or country initiating the action has allies, whether allies will intervene on either side, and the military strength or weakness of allies.

The factor most easily defined is the objective. The objective is the reason for military intervention. Objective, in Sullivan's model, is based on a continuum from "brute force" to "coercion." According to UGA News Service, the nature of the target is defined by the type of group which composes the target: guerilla, formal nation states, or terrorists. Examining these factors allows you to draw some conclusions about the odds of winning a military conflict.

Of the factors Sullivan identified the most important as whether the objective can be reached by military strength alone, or if target cooperation is essential in the military objective.

Sullivan explains that in the 1991 Gulf War Kuwait was a cooperative target. The citizens and government of Kuwait wanted the assistance of the United States. Driving out Hussein's forces was accomplished quickly and efficiently with the compliance of the nation of Kuwait.

Iraq has proven to be a different war story. Iraq did not invite the United States to enter their country. Although the United States entered on the stated premise of humanitarianism and a quest to end Hussein's reign of terror, that doesn't mean the U.S. was invited, and it doesn't mean the target is cooperative. The United States' objective to free the people of Iraq from the iron rule of Saddam Hussein and his Republican Guard was based on the plausible assumption that no human being wants to live in a state of suffering, euthanasia, and general brutality from a dictator. The United States government presumed the people of Iraq preferred freedom and democracy to the dictatorial, totalitarian government under which they lived. However, as a nation, Iraq has not proven cooperative to that objective.

Sectarian violence has kept the United States from meeting their military objective. Rather than welcoming international assistance in building a free nation, divided allegiances in the country have prolonged the military action. Many Muslim extremists view the United States as the face of the enemy, literally and spiritually. They continue to fight hard against governmental and social changes.

The lack of cooperation in Iraq is a huge indicator, according to Sullivan's model of the future of the war. It illuminates the need for target cooperation in military objectives. It does not, however, satisfy the question as to whether the probability of victory affirms or denies the call for military force to implement changes in the interest of humanitarianism.

Military force and humanitarianism, philosophically, should be mutually exclusive terms. However, often, in the face of brutality and oppression force is necessary to break the bonds of oppression. This creates a paradox which the United States government and citizens continue to grapple. It is, however, the same paradox that prompted the Declaration of Independence and the American Revolutionary War.

Sullivan reported to the UGA news service, "We can try to use brute force to kill insurgents and terrorists, but what we really need is for the population to be supportive of the government and to stop supporting the insurgents. Otherwise, every time we kill an insurgent or a terrorist, they're going to be replaced by others."

Once Sullivan developed her model, she tested it and found that her paradigm was accurate in 80% of the conflicts she examined, according to the UGA news service. Her model was used to examine the current war between the U.S. and its allies, and Iraq. Extrapolating an end to the war in Iraq based on Sullivan's model, theUGA news service estimates that there is a 26% chance of victory, in a war that could endure approximately ten years. Sullivan points out that factions, insurgents, and covert allies, such as Iran and Syria, seriously undermine the U.S. objective in Iraq.

Sullivan's conclusions regarding the war with Iraq were reported by the UGA news service as follows:

"No one could have predicted exactly what would happen after we overthrew the regime of Saddam Hussein," Sullivan said. "But what my model could say was that if the population was not supportive of whatever new regime we put in power and the American strategic objective shifted from regime removal to maintaining the authority of a new government, the likelihood of a successful outcome would drop from almost 70 percent to just under 26 percent."

Sullivan's research and reporting prove timely as the fierce debate over whether to pull our troops out of Iraq rages in the United States. According to Sullivan, the chances for the successful establishment of a new government in a free and independent Iraq are slim, without the cooperation of the Iraqis and surrounding nations. The research, however, does nothing to discourage those who believe in the fight in the name of higher moral law and justice.

Sullivan's paradigm is helpful, but must be weighed against the one's acceptance of age old adage, "It's not whether you win or lose, but how (or why) you play the game." One factor that Sullivan's research did not address includes an equation which may never be quantified: How much is one life worth in the pursuit of freedom and justice for all?

Sources:

Fahmy, Sam. "UGA study finds that weaker nations prevail in 39 percent of military conflicts, UGA Office of Public Affairs News Service, June 11, 2007.

http://www.uga.edu/news/artman/publish/070611_Sullivan.shtml

http://www.uga.edu/intl/sullivan.htm

http://jcr.sagepub.com/cgi/content/abstract/51/3/496





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stem cell research


The similarities between scientific research and criminal investigation are the search for the conclusion or a cause of the effect. Both scientists and criminal investigators are specially trained in their field of practice. They tend to use similar methods of research and investigation the cause. Scientists as well as investigators both observe the surroundings, the facts, the areas involved in the research or investigations. They classify the data into categories this can be as simple as determining if it is valid or not valid. There is the use of logic, the formation of a hypothesis or a theory as to why and what has occurred. Both sides must link information together to prove their hypothesis or conclusions. Both scientists and criminal investigators work in a systemic method which seeks accurate answers, not general conclusions.

So how can you tell which is which? It's not really that difficult once you understand the basic principles. Scientific research is a type of investigation which is systemic and basis its research on scientific methods which have been used in the past, and in relation to the scientific field. This type of research can be described as well organized, methodical, and precise. Scientists begin with an idea, a theory or a hypothesis. Scientists begin with an observation or description about what they intend to study/research. From these observations they form a hypothesis to explain their subject. They use the hypothesis to predict what may happen in the course of the research. The scientist begins to experiment or run tests based on their predictions about the hypothesis. They may also collect data about their observations to show that the hypothesis is either valid or not.
.
Criminal investigations begin with gathering documents and information. They begin to evaluate the facts about the events, or the crime. They use a systemic method to observe the details of the crime, as in who what where when why and how. They begin to piece things together, by assembling the facts and determining if the evidence gathered is useful or not. The hypothesis begins to form at this point which helps to link all the information gathered to the crime. The hypothesis in this sense is used to create a theory as to what happened, and the ability to define what has occurred. The hypothesis is an important part of the criminal investigation. The reason is that the investigator must prove or disprove the theory/hypothesis. Even more important for the investigator is to find the missing pieces, that are not ready available at the time. The investigator must be able to draw conclusions about the events but they must also be able to prove that the events did in fact occur.




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365.14 (Blogging) by kpwerker





At first I didn't like my Blogger blog as much as I did my Wordpress blog. The only reason was because of the limited theme choices that are available within the Blogger site.

I discovered how easy it is to use templates that are available for free out on the internet for Blogger. I find that changing themes is much easier to do on Blogger than on Wordpress. There are a lot of free themes that are available for Blogger. I'm definitely into free. Although, if I really like something and use it a lot, I will send a payment to a software author. I think it's only fair to do this. A little monetary appreciation is always an incentive for someone to keep on creating useful and imaginative work, and it's the right thing to do.

To be fair, though, there are also tons of free themes out there for Wordpress. The comparison I am making here is between the free Blogger and Wordpress hosted sites.

You can do a search for free Blogger templates. There are a lot of them out there. Once you find something you like, and are comfortable that the site you are downloading from is safe, download your file. The file will be in zip format, so you will need to unzip the file to your computer.

Once the file is downloaded and unzipped to your computer, go to your blogger dashboard, choose layout, and then Edit HTML. I would suggest that you download your current full template before you make any changes. This option is given to you on the edit HTML page. That way if you run into a problem you will be able to restore your original template, and not lose your work.

Now that your original template is saved you can begin to upload your new template. Upload the new template file from your hard drive on the edit HTML page. You will choose the file that was extracted to your hard drive when you unzipped your downloaded file. The template file is in .xml format. When the file is uploaded the Blogger upload will ask if you want to install widgets. These will be any of the sidebar or text features that you had on your blog before the upload. If you want to include these, tell the uploader yes.

You will now be able to preview the blog to see how the new template will look. If you are satisfied with the new look, save the template and view your blog. I was thrilled with the template that I found. The default templates are pretty limited on Blogger and I didn't know how easy it was to have a more stylish look for my blog.

I had seen other Blogger blog sites that looked really nice, and didn't know how this was accomplished until I did a little research. I'm finding that I really like Blogger. You can have a cool looking theme and a free blog as well as monetize the site. You can't do that with the free Wordpress blogs at this time. Wordpress does not allow their hosted blogs to be monetized. Although, if you self host a Wordpress blog, you can monetize it.

For me, I find that the free themes for Blogger are quite easy to use. The Wordpress themes are pulled into your blog by an add themes feature. I found that if I pulled in too many themes, it made my blog page run sluggish. I didn't like having to pull in the themes and then previewing them before I installed. It seemed to take a lot of time. I found that the free Blogger themes worked better with the widgets that were previously installed. Not so with Wordpress. I have only found one theme that will work well with all that I have on my blog site. It's just been more difficult with Wordpress. It could be because there are so many widgets that you can download for Wordpress that it can make changing themes difficult. You might not agree, and if so let me know.

Note: Just recently Blogger has changed their template designer. They have upgraded their themes and they look really great. They now offer themes that have a nice design and colors to choose from. You can still, however, use the free themes that are available on the net. In fact you will get much more selection by searching out templates on the internet.

Sources:

Personal Experience



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research methods in physical activity


According to St. Jude Children's Research Hospital in Memphis, the National Institute of Allergy and Infectious Diseases (NIAID) will grant $23 million a year, for seven years, to six new Centers of Excellence for Influenza Research and Surveillance.

The ultimate goal of the Centers of Excellence is to help the federal government prepare for and respond to influenza outbreaks, especially those that may lead to pandemics or worldwide epidemics as has been feared since the initial outbreak of H5N1 (avian influenza A) in China in 1997. The centers will work with NIAID's influenza surveillance program, both in the U.S. and worldwide, to learn more about influenza viruses - specifically how they cause disease and how the human immune system responds to them.

The media report says that St. Jude will also be involved in basic research, as well as surveillance of viruses. Dr. Robert Webster is a member of the Infectious Diseases department at St. Jude. With respect to this new contract, he said, "There are a variety of viruses to monitor besides the well-known H5N1. For example, H7N7 infected chicken industry workers in the Netherlands; and H9N2, which circulates in many global avian populations, also sporadically appears in humans."

This is not the first contract that St. Jude has had with NIAID. In 1999, two years after the avian flu outbreak in Hong Kong, St. Jude was awarded an NIAID contract to watch and study aquatic birds, especially ducks, and birds in live markets in Hong Kong. During this time, St. Jude was also involved in training others in the techniques of animal influenza surveillance and developing tests to detect and identify viruses. As a result of this work, St. Jude was also able to provide the NIAID with seed vaccines.

The media report says that influenza viruses will be monitored in several states and in more than a dozen countries over the next seven years. St. Jude will also monitor children in Hong Kong hospitals who are there for influenza and conduct surveillance in Southeast Asia in cases where children have been hospitalized for severe acute respiratory syndrome (SARS).

Dr. Richard Webby is an assistant member in the Division of Virology in the Infectious Diseases department at St. Jude. In the media report, he said that St. Jude's selection as a Center of Excellence "recognizes both the enormous contribution that St. Jude has made over the last several decades in the study of animal influenza viruses, as well as our leadership role in this area." That contribution is expected to continue in that St. Jude will also be involved in evaluating anti-viral drug treatments and causes of drug resistance during its work in the NIAID- funded program.

The other five hospitals also designated as Centers of Excellence are the University of California in Los Angeles, the University of Minnesota in Minneapolis, Emory University in Atlanta, Mount Sinai School of Medicine in New York and the University of Rochester in Rochester, N.Y.

Source:

St. Jude media report, http://www.stjude.org/media/0,2561,453_2086_22870,00.html




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